Publisher Information: Oxford: E Theatro Sheldoniano, 1674-1675.
Willis, Thomas (1621-75). Pharmaceutice rationalis sive diatriba de medicamentorum operationibus in humano corpore [Vol. II: Pharmaceutice rationalis. . . pars secunda]. 2 vols., 4to. , 330, ; , 496, pp. Signature (c) in Vol. II misbound after signature g. 14 engraved plates (6 in Vol. I, 8 in Vol. II), engraved title vignettes. Oxford: Sheldonian Theatre, 1674-75. 203 x 148 mm. Calf ca. 1675, rubbed, rebacked, corners repaired. Light toning, scattered foxing but very good. Bookplate in each volume noting John Lawson’s gift of this copy to Sion College in 1705; Sion College stamp and withdrawal stamp on title versos.
First Quarto Edition. Willis’s last work deals with the anatomy and physiology of the thoracic and abdominal organs, and contains the first description of the superficial lymphatics of the lungs, the first clinical and pathological account of emphysema, and a clear and accurate description of pertussis (whooping-cough). The book also contains the first distinction between diabetes mellitus, characterized by glycosuria, from diabetes insipidus, in which sugar is not present in the urine. Willis noted that psychogenic factors, such as grief or sadness, could bring on diabetes. The second volume, published posthumously, includes a life of the author.
Three versions of Willis’s book were published simultaneously: A quarto version with the imprint of the Sheldonian Theatre in Oxford, another quarto version with the London imprint of Robert Scott added, and a duodecimo edition. Dictionary of Scientific Biography. Garrison-Morton.com 3926, 5086. Norman 2248. Wing W-2844; W-2846.Book Id: 44285