Publisher Information: Berlin: 1881.
Koch, Robert (1843-1910). Zur Untersuchungen von pathogenen Organismen. In: Mittheil. kais. Gesundheitsamte 1 (1881): 1-48. With: Ueber Desinfection. In: ibid.: 234-82. With: Die Aetiologie der Tuberkulose. In: ibid. 2 (1884): 1-88. Together 2 vols., 4to. , 399 ; , 499 pp. 27 plates (14 chromolithographed, 3 double-page). Berlin: A. Hirschwald, 1881-84. 307 x 218 mm. Original boards, cloth backstrips, rebacked retaining original spines, a little worn & chipped. Library stamps on titles, light browning, but very good. Boxed.
First Editions. Garrison-Morton 2495.1; 5636.1; 2331(n).
Many of the bacteriological studies for which Koch became famous were published in the Mittheilungen aus dem Kaiserlichen Gesundheitsamte, a "house organ" of the Imperial Department of Health where Koch had been appointed government advisor (Regierungsrat) in 1880. The first volume of the Mittheilungen is particularly rich in Koch material: it contains no fewer than five papers written or co-written by Koch, including his landmark "Zur Untersuchung von pathogenen Organismen," in which he described his development of the plate technique for cultivating-the first consistent method for obtaining pure cultures of virtually any species of bacteria. The remaining papers include Koch's "Ueber Desinfection," in which he demonstrated mercuric chloride's superiority to carbolic acid as a disinfectant, as well as his "Zur Aetiologie des Milzbrandes," a continuation of his anthrax studies, and two papers co-written with Wolffh¸gel, Gaffky and Loeffler on disinfection with hot air and steam.
Vol. II of the Mittheilungen opens with Koch's "Die Aetiologie der Tuberculose," an expanded account of his epochal discovery that tuberculosis is caused by a specific bacterium (Bacillus tuberculosis); this followed two years after Koch's preliminary announcement of the discovery in a paper of the same title, published in the Berliner klinische Wochenschrift 19 (1882). The 1884 paper records Koch's success in producing experimental tuberculosis in animals after cultivating the bacillus, and also announces what became known as "Koch's postulates" for isolating and testing a disease-causing organism. It was this paper, rather than the 1882 preliminary announcement, that was selected by the Grolier Club to represent Koch's achievement in its exhibit and catalogue of 100 Books Famous in Medicine. This volume of the Mittheilungen also contains "Experimentelle Studien Uber die kunstliche Abschwichung der Milzbrandbacillen und Milzbrandinfection durch Futterung," a paper on artificial attenuation of the anthrax bacillus co-written by Koch, Gaffky and Loeffler.
Koch was awarded the Nobel Prize in 1905, in a large part for his work on tuberculosis. DSB. Grolier Club, 100 Books Famous in Medicine, 80 (Tuberculose). Horblit, One Hundred Books Famous in Science, 60 (Pathogenen Organismen).Book Id: 36297