On certain functions of the spinal chord, with further investigations into its structure. By J. Lockhart Clarke, Esq. Communicated by Samuel Solly, Esq., F.R.S. pp. 347-356 in: Philosophical Transactions, Vol. 143, Part III.

Publisher Information: London: Taylor and Francis, 1853. Whole issue in original printed wrappers, mostly uncut & unopened. [iv] 311-561 [1] 15pp.; 7 plates (Plates XIX. - XXVI.)
Jacob Augustus Lockhart Clarke (1817-1880) was an English physician, physiologist, histologist and neurologist.

Clarke received his material edication at Guy's Hispital and St. Thomas's Hospital in London. He was liscenced by the Apothecaries Society and subsequently went to love with his mother at Pimlico, where he established a private practice. From 1851 to 1868, while Clarke was engaged in general practice and continuing his studies at St. George's Hospital, he conducted his now famous research on the central nervous system. “Most of his numerous works were published in in the Philosophical Transactions (1851, 53, 58, 59, 60, 65, 68), in the Proceedings of the Royal Society (1857, 61), the Microscopical Journal, British and Foreign Medical Review (1864) and others. His earlier works concern the anatomy and the physiology of the medulla oblongata and the spinal marrow as well as the brain. His discovery of the Clark's column, also designated nucleus dorsalis, was done in this period. His later research is more concerned with pathological studies in his special field. he also published on tetanus, diabetes, paraplegias of muscular atrophy.

Clarke was described as a man of the highest character, "with s singleness of purpose, of noble independence, honest and just, conscientious and intellectually keen, but with a singularly retiring and reserved disposition. He never acquired a large practice and is reputed not to have been well off financially.” (Whonamedit? Jacob Augustus Lockhart Clarke. Accessed 11/4/2022. ). Book Id: 50480

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